Prenatal Diagnosis and Management of Fetal Goiter Treated Successfully with Intra-Amniotic Levothyroxine

Goiter is an enlargement of the thyroid gland which can be associated with a number of complications both for mother and fetus. A 34-year-old pregnant woman with normal function was referred to our Department Obstetrics and Gynecology at Microcitemico Pediatric Hospital, Cagliari, suspected fetal goiter 32 gestational weeks. The case monitored regularly by ultrasound and treated successfully intra-amniotic levothyroxine (L-T4) administration. Fetal goiter observed decrease after this treatment and the ultrasound findings were also birth in subsequent follow-ups. Our report confirms feasibility conservative treatment L-T4, effectively prevent complications related to fetal goiter.